Thunar occasionally stops responding to mouse actions. It seems random, and it doesn't happen often. If I close the window and restart thunar, it works fine. I found the following bug report, but it's six years old.
https://bugs.launchpad.net/ubuntu/+sour ... bug/520118
I use detailed view and haven't tried switching it. I will try ctrl-1,2 or 3 next time it happens. Is anyone else having this problem?